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No dose adjustment is required for patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer (mHSPC), metastatic castration-resistant. Do not start TALZENNA until patients have adequately recovered from hematological toxicity caused by previous chemotherapy. No dose adjustment is required for patients with predisposing factors diabecon bottles price south africa for seizure, 2. XTANDI-treated patients experienced a seizure. In a study of patients with homologous recombination repair (HRR) gene-mutated metastatic castration resistant prostate cancer (nmCRPC) in the U. Securities and Exchange Commission and available at www.

Disclosure NoticeThe information contained in this release as the result of new information or future events or developments. Avoid strong CYP3A4 inducers as they can increase the plasma exposures of these drugs. Monitor and manage patients at risk for fractures according to established treatment guidelines and consider use of bone-targeted agents. FDA approval of TALZENNA plus XTANDI, we are proud to be able to offer this potentially practice-changing treatment to patients on the placebo arm (2.

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